Anti-Reflux Mucosectomy (ARMS) is an endoscopic procedure considered in selected patients with gastroesophageal reflux disease. The procedure is designed to improve the anti-reflux barrier at the gastroesophageal junction without an external surgical incision.

During ARMS, a controlled area of mucosa near the gastroesophageal junction is removed using endoscopic techniques. As the treated area heals, scar formation causes tissue contraction around the junction. This may help reduce the opening through which reflux occurs and improve the function of the natural anti-reflux mechanism.

Patient selection is important. Evaluation may include upper GI endoscopy, assessment for hiatus hernia, esophageal manometry and reflux testing such as 24-hour pH monitoring. ARMS is generally considered only after confirming that symptoms are related to reflux and that the anatomy is suitable for endoscopic treatment.

Possible risks include pain, bleeding, narrowing at the gastroesophageal junction and persistent or recurrent reflux symptoms. Follow-up after the procedure is therefore important to monitor healing and response to treatment.